EKATO

Ekato

Mixing Technology for Pharmaceutical Products

Agitators and Vacuum Processing Units

Decades of know-how in dispersing and mixing technology as well as depth knowledge in all disciplines of process engineering at EKATO GROUP form the basis for the successful use of EKATO technology in the pharmaceutical industry.
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EKATO SYSTEMS for the Production of Ointments, Cremes, and Gels

Pharmaceutical products place a unique set of demands on agitators. The highest standards must be met. This applies to hygiene, the specialized processes employed, and the certified systems in use. Companies from the pharmaceutical industry benefit from EKATO SYSTEMS many years of experience and vast expertise in the production of equipment for the personal care and healthcare industry. In addition to the dryers and mixers offered in the product portfolio of SOLIDMIX, e.g. to dry active pharmaceutical substances, the product basket of UNIMIX covers the production of ointments, creams and gels that are used in the pharmaceutical industry. Reproducibility with respect to the production of pharmaceutical products is ensured based on system components that have been developed applying engineering expertise. Its mixers and dispersers in particular have been designed to ensure product stability and a uniform distribution of APIs in the product. Agitator systems play a central role in the production of APIs. The biotechnological production and hydrogenation of intermediate and finished products also place unique demands on the agitator systems. EKATO Rühr- und Mischtechnik GmbH works in the field of hydrogenation for over 90 years and offers specially designed hydrogenation plants for pharmaceutical applications.

In addition to the challenging tasks of active pharmaceutical ingredient synthesis production, the EKATO GROUP can also cover the area of industrial agitators in the pharmaceutical industry through the mixing and dispersing technology of EKATO FLUID GmbH. Mixing tasks can be suspending solids in a liquid phase, heating and cooling or mixing liquids. These mixing tasks are often part of the starting materials or storage of intermediate and final products.

Scale-up capability of the technology is crucial. To achieve this, algorithms are applied that have been specifically developed and verified many times. The systems and equipment are subjected to an established certification process to ensure top product quality.

 

Typical Project Process Flow

  • Concept phase
  • Design phase
  • Execution- and manufacturing phases
  • Test phase

We support by our consulting competencies in all project phases beginning from an URS to a functional specification, execution specification, production and installation of the plant, including the necessary qualification, for example

  • Design Qualification (DQ)
  • Installation Qualification (IQ)
  • Operational Qualification (OQ)
  • Support during Performance Qualification (PQ)

A crucial point is an early involvement and integration to the customers projects process to deliver the right package fitting customers’ needs.

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UNIMIX vacuum processing system

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Industrial Agitators EM

Designed for a large volume range and vessels with/without pressure. The drive unit can be directly driven by a motor or together with a gearbox.

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Laboratory Mixer & Dryer for Solids - SOLIDMIX

Compact laboratory system for mixing and drying trials with reliable scale‑up to production.

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EKATO Rühr- und Mischtechnik GmbH (EKATO RMT)

Focus: High-performance agitators, reactor agitators, process plants, mechanical seals
Typical Applications:

  • Chemical industry (specialty, polymer, bulk chemicals)
  • Pharmaceutical industry
  • Hydrometallurgy
  • Flue gas desulfurization
  • Biotechnology
  • Paints and coatings

Products & Services:

  • Customized agitators and impellers
  • Reactor agitators (e.g., coaxial, magnetic agitators)
  • Mechanical seals and seal supply systems
  • Process and pilot plants
  • CFD/FEA simulations, scale-up, engineering support
  • Global service network including maintenance, training, spare parts management

EKATO Systems GmbH

Focus: Vacuum processing units for liquids and solids (UNIMIX & SOLIDMIX)
Typical Applications:

  • Cosmetics industry
  • Pharmaceutical industry
  • Food industry
  • Chemical industry

Products & Services:

  • UNIMIX: Vacuum processing mixers for liquid to highly viscous products
  • SOLIDMIX: Solid mixers and dryers for powders and granules
  • Laboratory and pilot-scale systems (3–1000 liters)
  • GMP-compliant turnkey solutions including automation
  • Process consulting, development, scale-up, commissioning, maintenance

EKATO Fluid GmbH

Focus: Standardized, cost-effective industrial agitators
Typical Applications:

  • Chemical industry
  • Paints and coatings
  • Biotechnology
  • Biofuels
  • Pharmaceuticals
  • Cosmetics
  • Water and wastewater
  • Food industry
  • Pulp and paper
  • Fertilizers

Products & Services:

  • Top-entry and side-entry agitators (e.g., EM 2000, ES 2000, MD/SD)
  • Solutions for storage tanks, open and closed vessels
  • Simple mechanical seals
  • Short delivery times, high cost-efficiency
  • On-site commissioning and service

What does “Number of sealing faces” mean?

Single-acting mechanical seals
These seals have one sealing surface and only seal in one direction. They are generally simpler in design and are commonly used in applications where pressure is applied from only one side.

Double-acting mechanical seals
These seals have two sealing surfaces and can seal in both directions. They are ideal for applications where pressure may come from both sides or where a higher sealing performance is required.

Triple-acting mechanical seals
These are less common and used in specialized applications that require a more complex sealing setup. They offer additional sealing surfaces or mechanisms to ensure reliable sealing even in highly demanding environments.